C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/195 (2006.01) C07K 14/82 (2006.01)
Patent
CA 2608398
The present invention relates to cupredoxin, specifically Pseudomonas aeruginosa azurin, and/or Pseudomonas aeruginosa cytochrome c551 and their use in inhibiting of viral infection, and in particular infection of mammalian cells by the Human Immunodeficiency Virus (HIV). The invention also relates to variants and derivatives of cupredoxin and cytochrome c that retain the ability to inhibit viral infection, and in particular infection by the Human Immunodeficiency Virus (HIV). The invention also relates to research methods for studying viral and bacterial infection in mammalian cells.
L'invention concerne la cuprédoxine, en particulier l'azurinepseudomonas aeruginosa et/ou le cytochrome c551 de pseudomonas aeruginosa, ainsi que leur utilisation pour inhiber une infection virale, et en particulier une infection de cellules de mammifère par le virus d'immunodéficience humain (VIH). L'invention concerne également des variants et des dérivés de cuprédoxine et de cytochrome c qui permettent d'inhiber une infection virale, et en particulier une infection provoquée par le VIH. L'invention concerne encore des méthodes de recherche pour étudier une infection virale et bactérienne dans des cellules de mammifère.
Chakrabarty Ananda
Chaudhari Anita
Das Gupta Tapas
Fialho Arsenio
Hong Chang Soo
Chakrabarty Ananda
Chaudhari Anita
Das Gupta Tapas
Fialho Arsenio
Hong Chang Soo
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