Compositions and methods for treating hyperimmune response...

A - Human Necessities – 61 – K

Patent

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A61K 39/395 (2006.01) A61K 39/40 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2449488

The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination with other drugs are described. Also disclosed in the invention are methods of applying a composition comprising interferon gamma antibodies topically to the eye to treat hyperimmune reactions, such as transplant rejection, autoimmune diseases of the eye, and ocular disorders incidental to or connected with autoimmune diseases.

La présente invention concerne des procédés et des compositions pour le traitement de réactions hyperimmunes de l'oeil, ainsi que la mise en oeuvre de ces procédés et l'utilisation de ces compositions. Ces compositions comprennent des anticorps dirigés contre l'interféron gamma seuls et en combinaison avec d'autres médicaments. L'invention concerne également des procédés d'application topique sur l'oeil d'une composition comprenant des anticorps dirigés contre l'interféron gamma pour traiter des réactions hyperimmunes, telles que le rejet d'une greffe, des maladies auto-immunes de l'oeil et des troubles oculaires résultant de maladies auto-immunes ou liés à de telles maladies.

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