Compositions and methods for treating immunoproliferatifs...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/28 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2564246

The present invention relates to methods of treating proliferative disorders, particularly immunoproliferative disorders such as NK-type LDGL, and methods of producing antibodies for use in therapeutic strategies for treating such disorders. Generally, the present methods involve the use of antibodies that specifically bind to receptors present on the surface of the proliferating cells underlying the disorders.

La présente invention concerne des méthodes de traitement de troubles prolifératifs, notamment, de troubles immunoprolifératifs, tels que LDGL de type NK, et des méthodes de production d'anticorps utilisés dans des stratégies thérapeutiques de traitement de tels troubles. Généralement, les méthodes de cette invention impliquent l'utilisation d'anticorps qui se lient spécifiquement aux récepteurs présents à la surface de cellules proliférantes signalant les troubles.

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