Compositions and methods for treating infections using...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61L 27/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 16/44 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2263799

Compositions and methods for treating infections, especially bacterial infections, are provided. Indolicidin peptide analogues containing at least two basic amino acids are prepared. The analogues are administered as modified peptides, preferably containing photo-oxidized solubilizer.

Compositions et méthodes pour traiter les infections, en particulier les infections bactériennes. Des analogues peptides d'indolicidine contenant au moins deux acides aminés basiques sont préparés et administrés sous forme de peptides modifiés contenant de préférence un agent de solubilisation photo-oxydé.

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