Compositions and methods for treating intracellular infections

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61K 31/438 (2006.01) A61K 31/496 (2006.01) A61K 31/498 (2006.01) A61K 31/7036 (2006.01) A61K 45/06 (2006.01) A61K 47/34 (2006.01) A61P 31/06 (2006.01)

Patent

CA 2340898

A method of treating or preventing an intracellular infection in an animal comprising administering a first effective amount of a suitable drug contained in first biocompatible microspheres that have a diameter of less than or equal to about 10 microns, wherein the first microspheres release the suitable drug upon administration at a first effective rate. A second set of microspheres greater than 10 microns in diameter may also be administered to provide continuing systemic release of the drug.

La présente invention concerne le traitement ou la prévention d'une infection intracellulaire chez un animal. On administre à cet effet une première quantité suffisante d'un médicament approprié contenu dans des premières microsphères biocompatibles d'un diamètre n'excédant pas environ 10 ñm. Ces premières microsphères libèrent avec un premier débit efficace le médicament approprié dès son administration. On peut également administrer un second ensemble de microsphères d'un diamètre supérieur à 10 ñm permettant de prolonger la libération systémique du médicament.

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