Compositions and methods for treating neoplastic diseases

Details Compositions and methods for treating neoplastic diseases Compositions and methods for treating neoplastic diseases

A - Human Necessities

61

K

A61K 31/397 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2588923

Disclosed herein are compositions and methods for treating neoplastic diseases. Included are compositions and methods that are effective against multiple myeloma cells resistant to conventional and bortezomib treatment. Furthermore, combination treatment with two different proteosome inhibitors is shown to be synergistic for treating multiple myeloma.

L'invention porte sur des compositions et des procédés destinés au traitement des maladies néoplastiques. Les compositions et procédés de l'invention sont efficaces contre les cellules des myélomes multiples résistant aux traitements habituels et au bortézomib. En outre, l'invention concerne un traitement de combinaison de deux inhibiteurs du protéosome différents qui déploient une synergie dans le traitement des myélomes multiples.

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