Compositions and methods for treating or preventing...

Details Compositions and methods for treating or preventing... Compositions and methods for treating or preventing...

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/085 (2006.01) A61K 39/09 (2006.01) A61K 39/38 (2006.01) A61K 39/385 (2006.01) C07K 1/00 (2006.01) C07K 16/00 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2504938

The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.

L'invention concerne des polypeptides, des conjugués de polysaccharides-polypeptides, et des vecteurs d'expression utilisés dans le traitement ou la prévention d'une infection à pneumocoques. Les compositions de l'invention induisent une réponse immunitaire anti-pneumocoques lorsqu'elles sont administrées à un mammifère. Ces compositions peuvent être utilisées dans un but prophylactique pour vacciner un individu, et/ou thérapeutique pour induire une réponse immunitaire thérapeutique chez un individu infecté.

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