A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/06 (2006.01) A61K 31/435 (2006.01) A61K 31/437 (2006.01) A61K 31/7056 (2006.01) A61K 38/21 (2006.01) A61P 31/14 (2006.01)
Patent
CA 2597213
The present disclosure relates generally to compositions having a glucosidase inhibitor (castanospermine or a derivative thereof, such as celgosivir) in combination with adjunctive therapies of compounds that alter immune function (such as interferon) and compounds that alter viral replication (such as nucleoside analogues like ribavirin), which can be used to treat or prevent infections caused by or associated with a virus of the Flaviviridae family, particularly infections caused by or associated with Hepatitis C virus (HCV).
L'invention concerne, de manière générale, des compositions contenant un inhibiteur de la glucosidase (la castanospermine ou un dérivé de celle-ci, tel que le celgosivir) combinées à des traitements d'appoint de composés qui modifient la fonction immunitaire (tel que l'interféron) et de composés qui modifient la réplication virale (tels que des analogues de nucléoside du type ribavirine) pouvant être utilisés pour traiter ou prévenir des infections entraînées par un virus de la famille des Flaviviridae ou associées à celui-ci, en particulier, des infections entraînées par le virus de l'hépatite C (VHC) ou associées à celui-ci.
Clement Jacob
Dugourd Dominique
Friedland Hillel David
Rubinchik Evelina
Migenix Inc.
Smart & Biggar
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