Compositions and methods for treating or preventing glaucoma...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/00 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 45/06 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2661607

A composition for treating or preventing glaucoma or its progression comprises a dissociated glucocorticoid receptor agonist ("DIGRA"), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester thereof. The composition can comprise an additional anti-inflammatory agent and can be formulated for topical application, injection, or implantation. It may be used in combination with another therapy directed to reducing intraocular pressure.

L'invention concerne une composition de traitement ou de prévention du glaucome ou de son évolution. Cette composition contient un agoniste du récepteur de glucocorticoïde dissocié ('DIGRA'), un promédicament, un sel ou un ester pharmaceutiquement acceptables de celui-ci. La composition selon l'invention peut contenir un anti-inflammatoire supplémentaire et elle peut être préparée pour une application topique, une injection ou une implantation. Elle peut être utilisée en association avec un autre traitement visant à réduire la tension intraoculaire.

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