Compositions and methods for treating polycystic kidney disease

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61K 31/10 (2006.01)

Patent

CA 2648407

Disclosed herein are methods and compositions for the treatment of polycystic kidney disease or other diseases that are associated with alteration, either directly or indirectly, by tumor necrosis factor-alpha (TNF-.alpha.) of receptor-calcium channel complexes or calcium regulation such that cyst formation is stimulated.

L'invention concerne des méthodes et des compositions permettant de traiter une polykystose rénale ou d'autres maladies associées à une dégradation engendrée directement ou indirectement par le facteur de nécrose tumorale alpha (TNF-.alpha.) de complexes du canal calcique récepteur ou de la régulation calcique, de manière à stimuler la formation kystique.

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