A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/198 (2006.01) A61K 31/00 (2006.01) A61K 31/375 (2006.01) A61P 15/10 (2006.01)
Patent
CA 2419404
Methods for treating sexual dysfunction are disclosed. The methods generally comprise the administration of an NO donor and an antioxidant; the active ingredients can be administered topically to the genitals of the patient. The methods allow for localized NO delivery through topical application of the present compounds, while minimizing, if not preventing, damage associated with peroxynitrite formation. Compositions comprising L-arginine, or a derivative thereof and an antioxidant in a pharmaceutical carrier suitable for application to the genitals is also disclosed.
L'invention concerne des méthodes de traitement de dysfonctionnements sexuels. Les méthodes consistent généralement à administrer un donneur de NO et un antioxydant. Les principes actifs peuvent être administrés de manière topique aux organes génitaux du patient. Les méthodes permettent une administration localisée de NO par application topique des présents composés, tout en réduisant, voire en prévenant, les dommages associés à la formation de peroxynitrite. L'invention concerne également des compositions renfermant de la L-arginine ou un dérivé de cette dernière et un antioxydant dans un excipient pharmaceutique indiqué pour une application aux organes génitaux.
Sacks Meir S.
Van Dyke Knox
Sacks Meir S.
Smart & Biggar
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