A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7024 (2006.01) A61P 3/10 (2006.01) C07H 13/08 (2006.01)
Patent
CA 2458782
A partially purified plant extract for treating subjects who are hyperglycemic is provided. The partially-purified plant extract comprises a plurality of water soluble compounds having a molecular weight greater than 800 and less than 1500 grams/mole. One of the compounds in the partially-purified plant extract is the hydrolysable gallotannin known as penta-O-galloyl-D-glucose. The partially-purified plant extract is substantially free of triterpenoids, including corosolic acid and high molecular weight ellagitannins, i.e., ellagitannins having a molecular weight of greater than 1500 grams/mole. In a highly preferred embodiment, the partially purified plant extract is derived from the tropical plant Lagerstroemia Speciosa. L, which is also known as banaba. The present invention also relates to a method of using the present partially-purified extract to treat subjects who are hyperglycemic.
L'invention concerne un extrait de plantes partiellement purifié permettant de traiter des sujets atteints d'hyperglycémie. Cet extrait de plantes partiellement purifié comprend une pluralité de composés hydrosolubles ayant un poids moléculaire supérieur à 800 et inférieur à 1500 grammes/mole. L'un des composés de l'extrait de plantes partiellement purifié est le gallotannin hydrolysable, connu sous le nom de penta-O-galloyl-D-glucose. L'extrait de plantes partiellement purifié est sensiblement dépourvu de triterpénoïdes, notamment d'acide corosolique et de tanins ellagiques à poids moléculaire élevée, c'est-à-dire des tanins ellagiques ayant un poids moléculaire supérieur à 1500 grammes/mole. Dans un mode de réalisation idéal, ledit extrait de plantes partiellement purifié est dérivé de la plante tropicale Lagerstroemia Speciosa L, également connue sous le nom de banaba. L'invention concerne également une méthode d'utilisation dudit extrait de plantes partiellement purifié afin de traiter les sujets atteints d'hyperglycémie.
Chen Xiaozhuo
Li Jing
Li Yungsheng
Liu Fang
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Ohio University
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