Compositions and methods for treating thrombocytopenia

Details Compositions and methods for treating thrombocytopenia Compositions and methods for treating thrombocytopenia

A - Human Necessities

61

K

A61K 31/496 (2006.01) A61K 45/00 (2006.01) A61K 45/08 (2006.01) A61P 7/00 (2006.01) G06Q 90/00 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) G06Q 50/00 (2006.01)

Patent

CA 2628848

The present invention in certain embodiments is directed to a pharmaceutical dosage form comprising a therapeutically effective amount of a first agent that agonizes a human TPO receptor by binding to the rhTPO binding site of the human TPO receptor; and a therapeutically effective amount of a second agent that agonizes the human TPO receptor by binding to a binding site of the human TPO receptor distinct from the rhTPO binding site.

L'invention concerne, dans certains modes de réalisation, une forme posologique pharmaceutique qui comprend une dose thérapeutiquement efficace d'un premier agent agonisant un récepteur de TPO humain en se liant au site de liaison de rhTPO du récepteur de TPO humain, et une dose thérapeutiquement efficace d'un second agent agonisant le récepteur de TPO humain en se liant à un site de liaison du récepteur de TPO humain différent du site de liaison de rhTPO.

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