Compositions and methods for treating tumor cells

Details Compositions and methods for treating tumor cells Compositions and methods for treating tumor cells

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2209989

Antisense molecules, compositions thereof, and vectors encoding antisense RNA, and methods of using antisense molecules, compositions, and vectors for treating human glioblastoma cells in order to suppress the growth of the cells. The antisense molecules are substantially complementary to human fibroblast growth factor receptor gene one (the FGFR1).

L'invention porte sur des molécules antisens, des compositions les incluant, des vecteurs codant pour de l'ARN antisens et des méthodes d'utilisation desdites molécules et compositions et desdits vecteurs pour traiter les cellules de glioblastomes afin d'en inhiber la croissance. Lesdites molécules antisens sont sensiblement complémentaires du gène N·1 du récepteur du facteur de croissance de fibroblaste.

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