Compositions and methods for treating tumors presenting...

A - Human Necessities – 61 – K

Patent

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A61K 39/00 (2006.01)

Patent

CA 2623497

The present invention provides vaccine compositions stimulating in a human an immune response to human survivin, thus attacking tumor diseased cells overexpressing survivin. In particular, the present invention provides vaccine compositions comprising peptides derived from non-mammalian survivin as well as from modified mammalian, especially human survivin.

L'invention concerne des compositions de vaccin stimulant chez un humain une réponse immunitaire à la survivine humaine, attaquant ainsi les cellules atteintes de tumeur et surexprimant la survivine. L'invention concerne en particulier des compositions de vaccin contenant des peptides dérivés de survivine n'appartenant pas à des mammifères et de survivine modifiée de mammifères, notamment de survivine humaine.

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