Compositions and methods for treatment of hepatitis c...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/00 (2006.01) A61K 31/70 (2006.01) C07K 14/18 (2006.01) C12N 7/06 (2006.01) C12N 15/11 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2143678

Antisense oligonucleotides are provided which are complementary to at least a portion of HCV RNA and specifically hy- bridizable therewith. These oligonucleotides can be administered to inhibit the replication of Hepatitis C virus in vivo or in vitro and to treat Hepatitis C virus-associated disease. These compounds can be used either prophylactically or therapeutically to re- duce the severity of diseases associated with Hepatitis C virus.

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