C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/38 (2006.01) A61K 31/7088 (2006.01) A61K 39/245 (2006.01) A61K 39/395 (2006.01) C07K 14/035 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/571 (2006.01)
Patent
CA 2499995
The instant invention relates to antigens and nucleic acids encoding such antigens obtainable by screening a herpesvirus genome, in particular an HSV-1 genome. In more specific aspects, the invention relates to methods of isolating such antigens and nucleic acids and to methods of using such isolated antigens for producing immune responses. The ability of an antigen to produce an immune response may be employed in vaccination or antibody preparation technique.
La présente invention concerne des antigènes et des acides nucléiques codant ces antigènes, obtenus par criblage d'un génome du virus de l'herpès, notamment un génome de HSV-1. Selon des aspects plus spécifiques, cette invention concerne des procédés pour isoler de tels antigènes et acides nucléiques et des procédés pour utiliser de tels antigènes isolés afin de produire des réponses immunitaires. Le pouvoir d'un antigène à produire une réponse immunitaire peut être utilisé dans des techniques de vaccination ou de préparation d'anticorps.
Hale Katherine S.
Johnston Stephen A.
Sykes Kathryn F.
Board Of Regents The University Of Texas System
Kirby Eades Gale Baker
Macrogenics Inc.
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