Compositions and methods for treatment of mitochondrial...

C - Chemistry – Metallurgy – 07 – H

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C07H 19/067 (2006.01) A61K 31/7068 (2006.01) A61K 31/7072 (2006.01) A61P 21/00 (2006.01) A61P 25/28 (2006.01) C07H 19/06 (2006.01)

Patent

CA 2341700

Compounds, compositions, and methods are provided for disorders related to mitochondrial dysfunction. The methods comprise administering to a mammal a composition containing pyrimidien nucleotide precursors in amounts sufficient to treat symptoms resulting from mitochondrial respiratory chain deficiencles.

On décrit des composés, des compositions et des procédés qu'on utilise pour traiter les troubles associés au dysfonctionnement des mitochondries. Les procédés consistent à administrer à un mammifère une composition contenant des précurseurs nucléotidiques en quantité suffisante pour traiter les symptômes résultant de déficiences de la chaîne respiratoire mitochondriale.

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