Compositions and methods for treatment of ophthalmic...

A - Human Necessities – 61 – K

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A61K 31/21 (2006.01) A61K 31/16 (2006.01) A61K 31/215 (2006.01)

Patent

CA 2640151

Provided herein are compositions and methods for treating ophthalmic diseases and disorders. Compositions comprising retinylamine derivative compounds provided herein are useful for treating and preventing ophthalmic diseases and disorders, including diabetic retinopathy diabetic maculopathy, diabetic macular edema, retinal ischemia, ischemia-reperfusion related retinal injury, and metabolic optic neuropathy.

L'invention concerne des compositions et des méthodes pour traiter des maladies et des troubles ophtalmiques. Lesdites compositions comprennent des composés dérivés de la rétinylamine et sont utilisées pour traiter et prévenir des maladies et des troubles ophtalmiques, y compris une rétinopathie diabétique, une maculopathie diabétique, un AEdème maculaire diabétique, une ischémie rétinienne, une lésion rétinienne d'ischémie de reperfusion, et une neuropathie optique métabolique.

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