G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) A61K 38/04 (2006.01) A61P 7/02 (2006.01) C07K 5/087 (2006.01) C07K 5/103 (2006.01) C07K 5/113 (2006.01) C07K 7/06 (2006.01) C12Q 1/56 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2454418
The application describes ligands for binding targets, the ligands preferably including peptides having at least one sulfated or sulfonated amino acid. The ligand preferably specifically binds to heparin binding sites of biomolecules. Compositions, systems, and methods for making and using the ligands are described.
La présente invention concerne des ligands pour lier des cibles, ces liants comprenant, de préférence, des peptides présentant au moins un acide aminé sulfoné ou sulfaté. Ce liant se lie, de préférence, aux sites de liaison héparine des biomolécules. L'invention traite aussi de compositions, systèmes et procédés pour fabriquer et utiliser ces liants.
Hubbell Jeffrey A.
Maynard Heather D.
Schoenmakers Ronald
Ecole Polytechnique Federale de Lausanne (efpl)
Eidgenoessische Technische Hochschule Zurich (ethz)
Macpherson Leslie & Tyerman Llp
University Of Zurich
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