Compositions and methods for visualizing and eliminating...

A - Human Necessities – 61 – K

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Details

A61K 38/22 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2753804

The present invention relates generally to the field of cancer diagnosis and treatment, and more particularly to compositions and methods that may be useful for eliminating cancer cells with stem-like characteristics. The disclosed compositions and methods may also be useful for managing breast cancer, ovarian cancer, cervical cancer or endometrial (uterine) cancer with metastases; and visualizing the cancer cells in patient's body. The compositions of the instant invention include human prolactin receptor antagonist G129R.

La présente invention concerne d'une manière générale le domaine du diagnostic et du traitement du cancer et, plus particulièrement, des compositions et des procédés pouvant être utiles pour éliminer des cellules cancéreuses possédant des caractéristiques de type souche. Les compositions et procédés décrits peuvent également être utiles pour gérer un cancer du sein, un cancer de l'ovaire, un cancer du col de l'utérus ou un cancer de l'endomètre (utérin) avec des métastases, ainsi que pour visualiser les cellules cancéreuses dans le corps de la patiente. Les compositions de la présente invention comprennent un antagoniste du récepteur de la prolactine humaine G129R.

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