A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 9/16 (2006.01)
Patent
CA 2599585
The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or about, the density of the one or more microbeads comprising a thixotropic agent, water and one or more preservatives under conditions that reduce bubble formation and mixing the microbeads and the thixotropic solutions in a mixer that lacks scraping paddles.
La présente invention concerne des compositions et des procédés qui assurent la libération retardée des agents actifs présents dans une formulation liquide à longue durée de conservation. Le procédé de préparation consiste à mélanger au moins une microbille à libération contrôlée renfermant un ou plusieurs agents actifs, à préparer une solution thixotrope dense d'une densité égale ou similaire à la densité de la microbille renfermant un agent thixotrope, de l'eau et un ou plusieurs conservateurs dans des conditions qui réduisent la formation de bulles et à mélanger les microbilles et les solutions thixotropes dans un dispositif mélangeur dépourvu de palettes de raclage.
Lockhart Daniel
Mcmahen Russell Lee
Taskey Paul
Tengler Mark
Neos Therapeutics Lp
Shapiro Cohen
LandOfFree
Compositions and methods of making sustained release liquid... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods of making sustained release liquid..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods of making sustained release liquid... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1756807