C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) C12N 15/62 (2006.01)
Patent
CA 2571942
The present invention provides compositions and methods useful for purifying recombinant myelin-associated glycoprotein (MAG) and fragments thereof. In particular, the invention provides a one-step purification method for MAG and MAG fragments. Novel forms of human recombinant MAG protein are also disclosed in addition to methods of reliably producing and storing stable recombinant MAG proteins.
La présente invention concerne des compositions et des méthodes utiles pour purifier la glycoprotéine associée à la myéline (MAG) recombinée ainsi que des fragments de celle-ci. En particulier, l'invention concerne une méthode de purification en une étape de MAG et de fragments de MAG. L'invention concerne également de nouvelles formes de protéine MAG humaine recombinée en plus de procédés de production et de stockage fiables de protéines MAG stables recombinées.
Bates Brian
Campos Susie J.
Lu Zhijian
Mark Robert
Paulsen Janet E.
Torys Llp
Wyeth
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