Compositions and methods of tolerizing a primate to an antigen

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2514580

Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.

L'invention concerne l'induction de tolérance chez un mammifère à l'aide d'un composé ou d'une association d'au moins deux composés ayant certaines caractéristiques lorsqu'ils sont testés in vitro. Le composé, seul ou en association, est de préférence un anticorps TRX1 et le composé ou la combinaison est, de préférence, utilisé(e) conformément à un régime spécifique d'administration des doses.

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