Compositions and methods of treating cns disorders

A - Human Necessities – 61 – K

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A61K 31/495 (2006.01) A61K 45/06 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2655828

The invention relates to 5-HT6 receptor modulators. Compositions comprising arylamine compounds and acetylcholinesterase inhibitors and use of these compositions are disclosed. Such uses include e.g., the treatment, modulation and/or prevention of Alzheimer's disease and memory disorders, and psychological disorders such as schizophrenia, are disclosed.

La présente invention concerne des modulateurs des récepteurs 5-HT<SUB>6</SUB>. L'invention concerne des compositions comprenant des composés arylamines et des inhibiteurs d'acétylcholinestérase et l'utilisation de ces compositions. De telles utilisations de l'invention comprennent, par exemple, le traitement, la modulation et/ou la prévention de la maladie d'Alzheimer et de troubles de la mémoire et de troubles psychologiques tels que la schizophrénie.

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