Compositions and methods of treatment of cancer

A - Human Necessities – 61 – K

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Details

A61K 31/517 (2006.01) A61K 31/17 (2006.01) A61K 31/401 (2006.01) A61K 31/403 (2006.01) A61K 31/475 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2459583

This invention generally relates to compositions and methods for cancer treatment and, in particular, to compositions able to interact (e.g.,bind to) with MUC1 growth factor receptor or its ligands, and methods for treating the same. The invention also relates to assays or use of such compositions for the treatment of patients susceptible to or exhibiting symptoms characteristic of cancer or tumorigenesis. Other compositions of the present invention useful for the treatment or prevention of cancer or tumorigenesis include homologs, analogs, derivatives, enantiomers or functional equivalents. The present compositions can also be packaged in kits in some cases.

L'invention concerne de manière générale de compositions et de méthodes de traitement anticancéreux, et en particulier des compositions capables d'interagir (p. ex. de se lier) avec le récepteur du facteur de croissance MUC1 ou ses ligands, et des méthodes permettant de traiter ces derniers. L'invention concerne en outre des méthodes d'analyse ou d'utilisation de ces compositions pour le traitement de patients suceptibles de présenter ou présentant des symptômes caractéristiques d'un cancer ou d'une tumorigenèse. L'invention concerne également d'autres compositions servant au traitement ou à la prévention des cancers ou de la tumorigenèse. Ces autres compositions comprennent des homologues, des analogues, des dérivés, des énantiomères ou des équivalents fonctionnels. Dans certaines formes de réalisation, ces compositions peuvent également être conditionnées sous forme de trousse..

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