Compositions and methods of use of orf1358 from...

Details Compositions and methods of use of orf1358 from... Compositions and methods of use of orf1358 from...

A - Human Necessities

61

K

A61K 39/09 (2006.01) A61P 31/04 (2006.01) C07K 14/315 (2006.01)

Patent

CA 2728308

The present invention relates to polynucleotides encoding Streptococcus group C and G polypeptides and their use in immunogenic compositions. The invention also relates to immunogenic compositions comprising polypeptides encoded by those polynucleotides. In addition, the invention relates to methods of inducing an immune response in mammals against beta hemolytic Streptococcus or beta hemolytic Streptococcus infection using immunogenic compositions of the Streptococcus group C and G polypeptides and polynucleotides.

L'invention concerne des polynucléotides codant des polypeptides de streptocoques des groupes C et G, et leur utilisation dans des compositions immunogènes. L'invention concerne également des compositions immunogènes comprenant les polypeptides codés par lesdits polynucléotides. En outre, l'invention concerne des procédés destinés à induire, chez des mammifères, une réponse immunitaire dirigée contre des streptocoques bêta-hémolytiques ou une infection à streptocoques bêta-hémolytiques, à l'aide de compositions immunogènes comprenant lesdits polynucléotides et polypeptides de streptocoques des groupes C et G.

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