A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/44 (2006.01) A61F 2/10 (2006.01) A61F 2/14 (2006.01) A61F 2/44 (2006.01) A61K 6/033 (2006.01) A61K 38/39 (2006.01) A61K 38/48 (2006.01) A61K 38/57 (2006.01) A61L 15/32 (2006.01) A61L 27/12 (2006.01) A61L 27/24 (2006.01) A61L 27/46 (2006.01) A61L 27/54 (2006.01) A61L 27/60 (2006.01) A61L 31/04 (2006.01) A61L 31/16 (2006.01) A61F 2/00 (2006.01) A61F 2/28 (2006.01)
Patent
CA 2509060
Compositions and devices including collagen and a metalloprotease inhibitor, and methods of making and using same. The compositions may further include hydroxyapatite. Within certain embodiments the MMPI is a Tissue Inhibitor of Matrix Metalloproteinas (e.g.,.TIMP-1, TIMP-2, TIMP-3 or TIMP-4). Within other embodiments, the MMPI is tetracycline, or an analog or derivative thereof (e.g., minocycline, or doxycline); a hydroxamate (e.g., BATIMISTAT, MARIMISTAT, or, TROCADE); RO-1130830, CGS 27023A, BMS-275291, CMT-3, SOLIMASTAT, ILOMASTAT, CP-544439, PRINOMASTAT, PNU-1427690, or SU-5402. In other aspects, the MMPI may be a polypeptide inhibitor (e.g., an inhibitor of a matalloprotease maturase), a mercapto-based compound, or a bisphosphanate.
Compositions et dispositifs comportant du collagène et un inhibiteur de métalloprotéases, ainsi que procédés de production et d'utilisation desdits compositions et dispositifs.
Gravett David M.
Hunter William L.
Maiti Arpita
Toleikis Philip M.
Angiotech International Ag
Barrigar Intellectual Property Law
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