Compositions and methods of using hexokinase v

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/48 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2519517

The current invention provides methods of identifying modulators of hexokinase V. Such modulators can be used for the treatment of diabetes or for delaying the onset of diabetes. The invention also provides methods of diagnosing diabetes or pre-diabetes and methods of making a prognosis based on the detection of hexokinase V nucleic acids and proteins.

L'invention concerne des procédés d'identification de modulateurs de l'hexokinase V. Ces modulateurs peuvent être utilisés pour le traitement du diabète ou pour retarder son apparition. L'invention porte également sur des procédés de diagnostic du diabète ou du pré-diabète et sur des procédés de diagnostic basés sur la détection de protéines et d'acides nucléiques d'hexokinase V.

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