Compositions and methods of using sirna to knockdown gene...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/713 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2670801

This invention describes compositions and methods using siRNA to target various genes expressed in cells of transplanted organs or tissues and/or genes expressed in the host to improve the success of the transplantation.

L'invention concerne des compositions et des procédés faisant appel à des ARNsi pour cibler divers gènes exprimés dans des cellules d'organes et/ou de tissus transplantés et/ou des gènes exprimés dans l'hôte pour améliorer le succès de la transplantation.

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