Compositions and methods of vascular injury repair

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/12 (2006.01) C12N 5/078 (2010.01) A61P 9/10 (2006.01) C12Q 1/22 (2006.01)

Patent

CA 2628712

The present invention relates to pharmaceutical compositions comprising a chemotactic hematopoietic stem cell product comprising an enriched population of CD34+ cells containing a subpopulation of cells having chemotactic activity, methods of preparing these compositions and use of these compositions to treat or repair vascular injury, including infarcted myocardium.

L'invention concerne des compositions pharmaceutiques comprenant un produit de cellule souche hématopoïétique chimiotactique comprenant une population enrichie de cellules CD34+ contenant une sous-population de cellules ayant une activité chimiotactique. L'invention concerne en outre des procédés de préparation de ces compositions et leur utilisation pour le traitement ou la réparation de lésions vasculaires, y compris du myocarde infarci.

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