Compositions and methods related to the minn1 tumor...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/47 (2006.01) A61K 48/00 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2431585

The present invention relates to Ras signalling effector proteins, tumor suppressors and apoptosis. Specifically, the present invention relates to the Ras effector and tumor suppressor gene and protein Minn1 and the regulation/induction of apoptosis. The invention provides compositions and methods for the treatment of cancer, and also relates to the analysis of Minn1 gene structure, transcription and expression.

L'invention concerne des protéines d'effecteur de signalisation de Ras, des suppresseurs de tumeur et l'apoptose. Elle concerne, plus particulièrement, l'effecteur de Ras, ainsi que le gène suppresseur de tumeur et la protéine Minn1 et la régulation/induction de l'apoptose. Elle concerne des compositions et des procédés servant à traiter le cancer et concerne également l'analyse de la structure du gène Minn1, sa transcription et son expression.

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