Compositions and methods relating to endothelial cell...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) A01N 37/18 (2006.01) A61K 38/00 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 29/00 (2006.01) A61P 31/04 (2006.01) A61P 43/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2482919

The invention relates to compositions and methods based on the characterization of an endothelial cell protein C receptor (EPCR) dependent signaling by activated protein C (APC) which acts through protease activated receptor 1 (PAR1).

L'invention concerne des compositions et des procédés se basant sur la caractérisation d'une signalisation dépendante du récepteur de cellule endothéliale à la protéine C (EPCR) par la protéine C activée (APC) qui agit à travers le récepteur 1 activé par protéase (PAR1).

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