Compositions and methods relating to novel compounds and...

C - Chemistry – Metallurgy – 07 – D

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C07D 243/24 (2006.01) A61K 31/5513 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/10 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2659549

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and related compounds and methods of using benzodiazepine derivatives and related compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like.

La présente invention concerne de nouveaux composés chimiques, des procédés permettant leur découverte, et leur utilisation thérapeutique. En particulier, la présente invention concerne des dérivés de benzodiazépine et des composés apparentés ainsi que des procédés d'utilisation des dérivés de benzodiazépine et des composés apparentés en tant qu'agents thérapeutiques destinés à traiter un certain nombre de pathologies associées à la régulation erronée des processus de l'apoptose, de l'auto-immunité, de l'inflammation, de l'hyperprolifération, et d'autres processus analogues.

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