Compositions and methods relating to orthogonal ribosome...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2614326

Orthogonal ribosome orthogonal mRNA pairs are provided, as are methods for their selection involving a novel positive-negative selection approach, and methods for their use. Also provided are cellular logic circuits involving orthogonal ribosomes.

L'invention concerne des paires d'ARNm orthogonales de ribosomes orthogonaux et des procédés de sélection de celles-ci consistant en une approche de sélection positive-négative et des procédés d'utilisation de celles-ci. L'invention concerne également des circuits de logique cellulaire impliquant des ribosomes orthogonaux.

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