Compositions and methods to control bleeding

Details Compositions and methods to control bleeding Compositions and methods to control bleeding

A - Human Necessities

61

K

A61K 38/36 (2006.01) A61K 9/127 (2006.01) A61K 35/14 (2006.01) A61K 38/37 (2006.01) A61K 38/48 (2006.01) C07K 14/755 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2444709

Disclosed are compositions for treating blood coagulation disorders and allows for manipulation of the blood coagulation cascade. More particularly the invention, relates to compositions for altering bleeding that include a mixture of at least one blood coagulation factor in a low dose and phospholipid vesicles. The invention has a variety of important uses including controlling bleeding in a mammal that has or is suspected of having a potentially life-threatening blood coagulation disorder.

L'invention concerne des compositions de traitement de troubles de la coagulation sanguine et permettant la manipulation de la cascade de la coagulation sanguine. Plus particulièrement, l'invention concerne des compositions destinées à modifier le saignement, lesquelles contiennent un mélange d'au moins un facteur de coagulation sanguine à faible dose et de vésicules phospholipidiques. L'invention présente une variété d'utilisation importante notamment pour régler le saignement chez un mammifère présentant ou soupçonné de présenter un trouble de la coagulation sanguine mettant potentiellement la vie en danger.

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