Compositions and methods to enhance reverse cholesterol...

A - Human Necessities – 61 – K

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A61K 45/00 (2006.01) A61P 9/00 (2006.01) A61K 31/506 (2006.01) C12N 5/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2654608

The present invention shows that pharmacological up regulation of SRB-1, ABC-A1 and LCAT genes collectively can be used to promote reverse cholesterol transport and increase circulating HDL cholesterol as treatment for atherosclerosis and related cardiovascular disorders.

Selon la présente invention, la régulation pharmacologique positive collective des gènes SRB-1, ABC-A1 et LCAT peut être utilisée pour favoriser le transport inverse du cholestérol des HDL circulant en tant que traitement de l'athérosclérose et des affections cardiovasculaires apparentées.

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