Compositions and methods to inhibit the activation of active...

Details Compositions and methods to inhibit the activation of active... Compositions and methods to inhibit the activation of active...

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/36 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) C12N 9/64 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2105863

2105863 9215609 PCTABS00016 Compositions and methods for inhibiting the activation and/or active state of a precursor protein are provided. Compositions provided can bind to a cleavage site of a precursor protein. Also provided are compounds useful for generating inhibitor compositions. Application of the invention to the treatment of myocardial infarction and other thrombotic conditions is specifically provided. Further provided are antibodies specific for active Factor XIII.

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