Compositions and methods to prevent and/or treat cancer with...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/78 (2006.01) A61K 38/44 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) C07K 14/21 (2006.01) C12N 9/02 (2006.01) C12N 15/55 (2006.01)

Patent

CA 2753121

The present invention relates to methods and materials for killing cancer cells with proteins derived from bacteria. The invention specifically relates to Azurin, Laz, Pa-CARD, and fusion proteins Azu-H.8 and H.8-Azu, and their use in killing leukemia cells and/or ovarian cancer cells.

La présente invention porte sur des procédés et des matières pour tuer les cellules cancéreuses avec des protéines issues de bactéries. L'invention porte spécifiquement sur Azurine, Laz, Pa-CARD et sur des protéines de fusion Azu-H.8 et H.8-Azu, et sur leur utilisation pour tuer des cellules de leucémie et/ou des cellules d'un cancer des ovaires.

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