C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/21 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 14/195 (2006.01) C07K 14/22 (2006.01) C07K 14/225 (2006.01) C07K 14/28 (2006.01) C12N 15/31 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2677803
The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The cargo compound may be a nucleic acid and specifically a DNA, RNA or anti-sense. The invention further discloses methods for treating cancer and diagnosing cancer.
La présente invention concerne des procédés et des matériaux destinés à fournir un composé transporteur dans une cellule cancéreuse. Afin de fournir ledit composé transporteur, on utilise des domaines de transduction de protéine dérivés de cuprédoxines. Ledit composé transporteur peut être un acide nucléique, et plus spécifiquement un ADN, un ARN ou un anti-sens. L'invention concerne en outre des procédés destinés au traitement du cancer et au diagnostic du cancer.
Beattie Craig
Chakrabarty Ananda
Das Gupta Tapas
Yamada Tohru
Smart & Biggar
The Board Of Trustees Of The University Of Illinois
LandOfFree
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