Compositions and methods using rna interference targeting...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/82 (2006.01)

Patent

CA 2676682

The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of genes essential to establishing or maintaining nematode infestation in a plant, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target plant gene, which is an MTHFR-like gene, and relates to the generation of plants that have increased resistance to parasitic nematodes.

La présente invention concerne des compositions d'ARN double brin ainsi que des plantes transgéniques pouvant inhiber l'expression de gènes essentiels à l'établissement ou à l'entretien d'une infestation par des nématodes chez une plante. L'invention concerne également des méthodes associées. Plus spécifiquement, l'invention concerne l'utilisation d'ARN interférence pour inhiber l'expression d'un gène de plante cible, qui est un gène du type MTHFR, et concerne la génération de plantes qui présentent une résistance accrue aux nématodes parasites.

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