Compositions and products containing enantiomeric equol, and...

Details Compositions and products containing enantiomeric equol, and... Compositions and products containing enantiomeric equol, and...

A - Human Necessities

61

K

A61K 31/353 (2006.01) A23L 1/30 (2006.01) C07B 57/00 (2006.01) C07D 311/58 (2006.01) C12P 17/06 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2492754

A composition for use in making commercial food and skin products comprising S- equol, or R-equol, or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, pharmaceuticals, and medicaments. The compositions are useful in a method of delivering S-equol to a mammal to prevent or treat a disease or associated condition, including hormone-dependent diseases or conditions such as cardiovascular disease, lipid disorder, osteopenia, osteoporosis, liver disease, and acute ovarian estrogen deficiency. The S-equol enantiomer can be produced in a biological synthesis from the metabolism of an isoflavone by an organism.

L'invention concerne une composition servant à la production de produits alimentaires et dermatologiques commerciaux, contenant S-équol ou R-équol ou des mélanges de ceux-ci se présentant sous la forme d'un mélange non racémique et d'un mélange racémique de S-équol et de R-équol. Ladite composition peut servir à la production de produits commerciaux tels que des additifs alimentaires, des agents pharmaceutiques et des médicaments. Lesdites compositions interviennent dans un procédé d'administration de S-équol à un mammifère pour la prévention ou le traitement d'une maladie ou de troubles associés, tels que des maladies ou troubles hormono-dépendants, troubles lipidiques, ostéopénie, ostéoporose, troubles hépatiques et déficiences oestrogéniques ovariennes graves. L'énantiomère de S-équol peut être fabriqué par synthèse biologique à partir du métabolisme d'une isoflavone par un organisme.

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