Compositions and their uses for lysosomal enzyme deficiencies

Details Compositions and their uses for lysosomal enzyme deficiencies Compositions and their uses for lysosomal enzyme deficiencies

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 36/06 (2006.01) A61K 47/36 (2006.01) A61P 3/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2580537

The present invention provides a composition comprising an extracted yeast cell wall comprising beta-glucan, a payload trapping molecule and a payload molecule, wherein the payload molecule and the payload trapping molecule are soluble in the same solvent system wherein the payload molecule supplements the function of the deficient lysosomal enzyme. The invention further provides methods of making and methods of using the composition.

L'invention concerne une composition qui renferme une paroi de cellule de levure extraite, à bêta-glucane, une molécule piégeuse de charge utile et une molécule de charge utile, ces deux molécules étant solubles dans le même système de solvant, sachant que la molécule de charge utile supplée la fonction de l'enzyme lysosomale déficiente. L'invention concerne enfin des procédés d'élaboration et d'utilisation de la composition.

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