A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/501 (2006.01) A61K 31/435 (2006.01) A61K 31/50 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2650711
The invention relates to compositions, conjugates and methods comprising pyridazine compounds and cholinesterase inhibitors for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
La présente invention concerne des compositions, des conjugués et des méthodes comprenant des pyridazines et des inhibiteurs de cholinestérase qui sont destinés à la modulation de voies cellulaires (par exemple de voies de transduction du signal), pour le traitement prophylactique ou thérapeutique de maladies inflammatoires (par exemple la maladie d'Alzheimer), ainsi que pour la recherche, le criblage de médicaments et pour des applications thérapeutiques.
Hu Wenhui
Van Eldik Linda
Watterson Martin
Mccarthy Tetrault Llp
Northwestern University
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