Compositions and use of epas1 inhibitors

Details Compositions and use of epas1 inhibitors Compositions and use of epas1 inhibitors

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2720473

The present invention relates to inhibitors of endothelial PAS domain protein 1(EPAS1), and methods and compositions related to the EPAS1 inhibitors. In certain embodiments, the EPAS1 inhibitors include nucleic acids, such as for example siRNAs.

La présente invention porte sur des inhibiteurs de la protéine du domaine PAS endothélial 1 (EPAS1), et sur des procédés et des compositions se rapportant aux inhibiteurs d'EPAS1. Dans certains modes de réalisation, les inhibiteurs d'EPAS1 comprennent des acides nucléiques, tels que, par exemple, des ARNsi.

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