Compositions and uses of a galectin for treatment of dry eye...

A - Human Necessities – 61 – K

Patent

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A61K 38/17 (2006.01)

Patent

CA 2604583

Methods for the therapeutic treatment of dry eye in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a galectin-1 protein, a galectin-3, a galectin-7 protein and/or a galectin-8 protein are provided. Pharmaceutical and ophthalmic compositions and kits, comprising a pharmaceutically an active agent which is a galectin-1 protein, a galectin-3 protein, galectin-7 protein and/or a galectin-8 protein, and a suitable carrier or a diluent, are provided.

L'invention concerne des méthodes de traitement thérapeutique de l'oeil sec chez des mammifères, lesquelles méthodes consistent à administrer à un mammifère souffrant d'une lésion épithéliale une quantité thérapeutiquement efficace de galectine-1, de galectine-3, de galectine-7 et/ou de galectine-8. Cette invention concerne également des compositions pharmaceutiques et ophtalmiques ainsi que des trousses contenant un agent pharmaceutiquement actif, à savoir la galectine-1, la galectine-3, la galectine-7 et/ou la galectine-8, ainsi qu'un excipient approprié ou un diluant.

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