Compositions and uses of dalbavancin for treatment of...

A - Human Necessities – 61 – K

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A61K 38/14 (2006.01) A61K 31/704 (2006.01) A61P 31/04 (2006.01) A61K 38/12 (2006.01)

Patent

CA 2506236

The invention provides methods and compositions for treatment of bacterial infections. Methods of the invention include administration of dalbavancin for treatment of a bacterial infection, in particular a Gram-positive bacterial infection of skin and soft tissue. Dosing regimes include once weekly administration of dalbavancin, which often remains at therapeutic levels in the bloodstream for at least one week, providing prolonged therapeutic action against a bacterial infection.

L'invention concerne des procédés et des compositions pour le traitement d'infections bactériennes. Les procédés de l'invention comprennent l'administration de dalbavancine dans le traitement d'une infection bactérienne de la peau et des tissus mous, notamment une infection bactérienne Gram-positif de la peau et des tissus mous. Le dosage de régimes comprend l'administration hebdomadaire de dalbavancine, qui reste à des niveaux thérapeutiques dans le flux sanguin pendant au moins une semaine, et fournit une action thérapeutique prolongée contre une infection bactérienne.

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