Compositions comprising 1-oxo- or thiohydrocarbyl...

A - Human Necessities – 61 – K

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167/159, 167/179

A61K 47/22 (2006.01)

Patent

CA 1337401

This invention provides compositions comprising a physiologically-active agent and a compound represented by the general formula Image wherein X may represent sulfur, oxygen or 2 hydrogen radicals; Y may represent -CH2-, -NH- or oxygen; n and m are integers of from 1 to 3; p is an integer of from 3 to 17; q is 2, 4, 6 or 8; and R' is selected from the group consisting of H, a lower alkyl group having from 1 to 4 carbon atoms, phenyl, lower alkyl or halogen substituted phenyl, acetamido, halogen, piperidinyl, lower alkyl or halogen substituted piperidinyl, carbalkoxy, carboxamide, and alkanoyl. These compositions are useful in topical or transdermal applications of the physiologically-active agent.

574417

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