A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/159, 167/215
A61K 47/22 (2006.01) A01N 37/18 (2006.01) A01N 43/60 (2006.01) C07D 295/185 (2006.01) D06M 16/00 (2006.01) D06P 1/642 (2006.01)
Patent
CA 1308352
ABSTRACT OF THE DISCLOSURE This invention provides compositions comprising a physiologically-active agent and a compound represented by the general formula Image wherein X may represent sulfur, oxygen or nitrogen; a and b may be 0 or 1, c may be 0, 1 or 2, except that when X is oxygen, a, b and c are 0, when X is nitrogen c is 0 and only one of a or b is 1, and when X is sulfur a and b are 0; A is a branched or a straight chain, divalent aliphatic radical having from 0 to 2 double bonds; R' is selected from the group consisting of H, a lower alkyl group having from 1 to 4 carbon atoms, phenyl, lower alkyl or halogen substituted phenyl, acetamido, halogen, piperldinyl, lower alkyl or halogen substituted piperidinyl, carbalkoxy, carboxamide, and alkanoyl; and R is hydrogen or a lower alkyl group having from 1 to 4 carbon atoms, Image Image or wherein R" is H or halogen, and salts, e.g. acid or quaternary derivatives, thereof. These compositions are useful in topical or transdermal applications of the physiologically-active agent.
538492
Minaskanian Gevork
Peck James V.
Gowling Lafleur Henderson Llp
Whitby Research Inc.
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