Compositions comprising a tramadol material and any of...

Details Compositions comprising a tramadol material and any of... Compositions comprising a tramadol material and any of...

A - Human Necessities

61

K

A61K 31/485 (2006.01)

Patent

CA 2077637

This invention relates to compositions comprising a tramadol material and any of codeine, oxycodone or hydrocodone, and their use. The compositions are pharmacologically useful in treating pain, diarrhea and tussive conditions. The compositions are also subject to less side-effects as compared to pure opiate based compositions, such as abuse liability, tolerance, constipation and respiratory depression. Furthermore, where the components, i.e., a tramadol material and any of codeine, oxycodone or hydrocodone, of the compositions are within certain ratios the pharmacological effects of the compositions are superadditive (synergistic).

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